Tuesday 22 January 2013

Can you be treated?

Treatment


A specific cure for patients with homocystinuria is not known. However, special diets and supplements will help people suffering from this disorder to cope.  

Vitamin B6 (pyridoxine) This is an important method. Close to half the people respond to vitamin B6. For children who show improvement from high doses of vitamin B6, this will help prevent mental retardation and behavior problems.

Those who benefit from vitamin B6 will have to take the supplements for the rest of their lives. Those who do not, have to follow a low methionine diet. 






Methionine diet. Patients must ingest food that has low methionine content. Patients must not have cow’s milk, regular formula, meat, fish, cheese, or eggs. Regular flour, dried beans, nuts, and peanut butter also contain methionine and must be avoided or strictly limited.





Medical diet. For children, they are given special medical formula instead of milk. This will help to correct the amount of proteins and nutrient. At the same time, keep the levels of methionine within the safe range. 


Betaine. Most will need to be treated with trimethylglycine (a medication also known as betaine). It is a vitamin-like substance that can be found in grains and be bought in pill form as a supplement. 
Betaine can help lower the amount of homocystine in the blood, and may be especially helpful for children who do not respond to vitamin B6. It may also lessen the risk of blood clots.   


Taking a folic acid supplement and adding cysteine (an amino acid) to the diet are helpful.

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